We have some good systems for a future A2/AD capability. EW systems like Koral-2, to ground attack missiles like Atmaca and Bora. But much more is needed for a full No-fly-zone, like a long range AAM and radar. But some important systems like Siper are in progress.
If we are abe to detect and track every start of aircrafts from GR soil, we can engage them with a missile. Before they start the mission. In the second stage, we can destroy the runways.