Let's say, hypothetically, that all of USA's Air Force Base access in Iraq, Kuwait, etc, were put out of commission and that the Saudis wanted to stay out of the war and didn't want USA launching strikes from their territory. I'll even got as far as suggesting that Turkey said the same thing make Incirlik a "no go" as well.
USA would still have the following options (just to mame a few) to launch hundreds of air sorties each day in support of Israeli air force and ground forces...
USS Dwight D Eisenhower
80 F-18F Super Hornets
USS George Washington
60 F-18F Super Hornets
20 F-35B Lightning II
USS Abraham Lincoln
60 F-18F Super Hornets
20 F-35B Lightning II
USS Wasp
20 F-35 Lightning II
Israeli Air Force Bases (Israel)
Aviano Air Force Base (Italy)
Akrotiri Air Force Base (Cypress)
NSA Souda Bay (Greece)
NSA Port Lyautney (Morocco)
Not to mention, USA has BY FAR the best air-to-air refueling capabilities in the world and could launch plenty of long range strike missions from as far away as Europe. They have more than 500 refueling aircraft that can extend the range of fighter / bombers by KMs of miles. They also have dozens of B-52s and B-1s and B-2s, with nearly unlimited range, that could be brought into theater from around the world.
USA could ABSOLUTELY keep hundreds of strike aircraft and long range bombers in the fight for an extended period of time (weeks at least) without the use of airfields in Iraq, Kuwait, Saudi Arabia, Turkey, Bahrain, etc... If some of those countries decide to allow USA use of their airfields because they want to see Iran hurt in the war, then it's not even close. USA would have all the airfields it would need to bring hundreds of quality combat aircraft into theater from around the world.
As always, Your numbers are inflated. US carrier wing consists of 44 fighters. Not 80, for good reason. Italy and Morocco is too far away and has no relevance for fighter ops. Bombers cam be flown from anywhere but those are stand-off. Keeping tankers over Syria and Lebanon is gonna be risky and require expanding the war to both countries.
And if we factor Israel in, then some of their air bases will also be crippled by Hezbollah. They have too many missiles and rockets.