Drones will dominate any 4th gen figther within 5 years and possibly 5th gen figther in 10 years. This is specially true for a country like USA which has all the infrastructure ready for this today. They have the drones, they have the sensors, they have the ammunition and most importantly, they have Starlink to control any drone around the world in real time with latency as low as 20-40ms and gigabit throughput. For the last second defence, current AI algorithms is more than enough to do evasive maneuvers requireing <1 ms response time, which is far faster than humans can do.
The second part people miss completely is that there is a hard requirement on manned figthers to be big, expensive and high-performance in order to protect the pilot. So fleets concentrate on a single high performance platform such as F16 or f35 as their main offensive figther. The only viable tactics for manned figthers is to be fast in, carry a lot of bombs and be fast out of the area of danger.
A drone does not have this requirement or limitation so you won't see a fleet with only high performance drones in offensive or defensive roles. You will see very small cheap stealth drones doing passive surveillance 50-200 km in front of your air-superiority fighters. These small surveillance drones does not even need to be required to survive. They just needs to be invisible to the enemy as long as possible. The figthers will then be followed with stealthy or heavy bombers. Finally, you will have heavy AWACS drones with very powerful radar as last line somewhere 200 to 300 km behind your small surveillance drones. All this for less than what a single modern high-performance figther cost today.
So manned drones are disadvantaged in tactics, sensors, ammunition, numbers and risk management. There is simply no possibility for manned figthers to survive against drones in the near future when the drones are designed for their specific tasks.
The real question is, will any other country outside USA have these in the near future. Yes, China in particular but Turkey is also on a good way to have this. Europe, not so much in the next 10 years.
Here are some link for what AI can do even for hobbyist today.
Besides these, all of you must have seen the swarms with 10000 drones. No human or group of humans can come close to control such swarms. These swarms will be deadly against any target whatsoever as there is simply no defence against them. Send in 1000 small drones against a aircraft carrier and it is 100% certain that the drones to win by blowing up all the sensors and weapons in the whole carrier group. The final blow to the carrier group will come from the bombers drones.